Heterochromatin Replication: Better Late Than Ever

Heterochromatin Replication: Better Late Than Ever

Different heterochromatic properties appear on satellite DNA during successive embryonic division cycles in Drosophila. One such property, late replication, precedes HP1 recruitment, is under the control of zygotic transcription, and helps to lengthen S phase.

Better Late Than Never

Some Prolog systems are able to delay the execution of Prolog goals and resume it later. We were involved in the design, implementation and evaluation of several such systems and we summarise here our experiences with them. First we describe a general structure of such ’coroutining’ systems and then we concentrate on the particular features of and choices made in three ECRC’s logic programming ...

Better late than never?

Although additional validation studies are needed, the data suggest that knowledge of circulating miRNAs such as miR-155 may someday be used to predict which patients with MBL go on to develop overt CLL. Importantly, the investigators looked at several types of specimens, including CLL cells and plasma from patients with CLL. Plasma miR-155 was as effective a biomarker as miR-155 isolated from ...

Replication: Needed Now More Than Ever.

Now, More Than Ever, Proteomics Needs Better Chromatography.

From plant research to biomedicine, proteome analysis plays a critical role in many areas of biological inquiry. Steady improvement in mass spectrometer (MS) technology has transformed the speed and depth of proteome analysis. Proteomes of simple organisms can now be sequenced to near completion in just over an hour. Comparable coverage of mammalian proteomes, however, still requires hours or e...